Glucosamine Sulfate

Glucosamine is an aminopolysaccharide (a combination of an amino acid - glutamine and a sugar - glucose). Glucosamine is concentrated in joint cartilage where it is incorporated in longer chains known as glycosaminoglycans and finally into very large structures known as proteoglycans. The proteoglycans function to attract water into the joint space for lubrication of the cartilage during movement.

There are numerous European studies showing a clear benefit of glucosamine supplements for relief of joint pain and stiffness associated with arthritis. Many of the studies have been criticized for lack of scientific control, short duration and small size, but recent meta-analyses of the smaller studies have supported the beneficial role of glucosamine supplements as a safe and effective approach to treating osteoarthritis. In general 1-3 months of glucosamine supplementation seems to be more effective than a placebo and at least as effective as analgesic and non-steroidal anti-inflammatory drugs (NSAID), like acetaminophen and ibuprofen, in reducing the joint pain of osteoarthritis.

As you age, the amount of glucosamine created by your body decreases. The result? Your cartilage and bones begin to scrape against each other, your joints become damaged, and the lubricating synovial fluid in your joint spaces becomes thin and watery.

All glucosamine supplements are NOT the same. To ensure effective absorption and tissue utilization, it's highly recommended that one takes glucosamine in the sulfate form. This is the way glucosamine is found in the body, and it lacks any known toxicity.

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